The World Health Organization 2019, report has stated that the non-communicable diseases are responsible for 70 % of deaths occurring due to chronic ailment, the remaining 30 % deaths are due to communicable diseases. Pharmaceutical industries are investing huge amount of revenue in the formulation and development studies to effectively deliver the drugs in human body. Excipients undergo tremendous scrutiny and modification to achieve desirable physical and chemical characterization of the drug formulations.
In the product segment for topical excipients inorganic chemicals and organic chemicals are studied. The inorganic chemicals consists of calcium phosphate, calcium carbonate, calcium sulfate, magnesium stearate, metallic oxides and others. Organic chemicals is segmented as starch, cellulose, petrochemicals, oleochemicals and other organic chemicals. Starch is further sub-segmented as modified starch, dried starch and converted starch. Cellulose includes cellulose ethers, microcrystalline cellulose, cellulose esters and CMC and croscarmellose sodium. Petrochemicals considered as topical excipients are the glycols, povidones, mineral hydrocarbons, acrylic polymers and other petrochemical excipients. Glycols comprises of polyethylene glycol and propylene glycols. Mineral hydrocarbons majorly comprises petrolatum, mineral waxes and mineral oils. Oleochemicals are further categorized as fatty acids, mineral stearate, glycerin and other oleochemicals excipients. The excipients find different functions in drug formulation such as buffers, adsorbents, permeation enhancers, surfactants, stabilizers, emulsifiers, preservatives, chelating agents, polymers, humectants and others. Market estimation and data mining is performed for the product and function segments respectively.
For the scope of the report market estimation and data mining is performed for the geography segments.
There is tremendous diversity in the topical excipients which are used in drug formulation, and hence it is very important to understand the competition existing in the topical excipients market. Market assessment gives a brief idea regarding the latest trend existing in the preference of excipients for drug formulation. Company profiles will furnish entire product range of the excipients and financial information of the companies. Manufacturers influencing the topical excipients market are Ashland, Inc., AkzoNobel, Roquette Group, BASF SE, J. M. Huber Corporation, The DOW Chemical Company, The Lubrizol Corporation, FMC Corporation, Evonik Industries AG, Merck Millipore, Associated British Foods Plc, Croda International Plc, Archer Daniels Midland Company, and Others.
Excipients are very important during the formulation of active pharmaceutical ingredient. It has an important role in delivering the drug in the human body. It has no medicinal properties but streamlines the production of drug molecules and promotes physical absorption of drug. They are useful in enhancing the physical properties of drug formulation such as disintegrating time, lubricant, flowability, taste masking etc. The organic chemicals are most frequently used excipients in drug formulation owing to its enhanced compatibility with the active pharmaceutical ingredient. Organic chemicals have undergone technical modification during the novel drug delivery studies thereby improving the flowability, drug absorption capacity, and disintegration time of drug formulation. Inorganic chemicals due to its inert nature are mostly used as fillers and taste masking agent in drug formulation. Manufacturers influencing the topical excipients market are Ashland, Inc., AkzoNobel, Roquette Group, BASF SE, J. M. Huber Corporation, The DOW Chemical Company, The Lubrizol Corporation, FMC Corporation, Evonik Industries AG, Merck Millipore, Associated British Foods Plc, Croda International Plc, Archer Daniels Midland Company and Others.
On the basis of functional properties of excipients they are utilized for making solid, semisolid and liquid drug formulation. Stabilizers and emulsifiers are mostly used in the semisolid and liquid dosage form. Stabilizers such as benzophenone and butylated hydroxytoluene derivatives are chemical moieties which prevents chemical, oxidative and light sensitive degradation of the active pharmaceutical ingredients. Emulsifiers such as lecithin and taurocholic acid enhances the miscibility of oil-liquid and liquid-gas phases to promote product shelf life and attain smooth drug delivery. Preservatives and buffers are mandatory excipients in a drug formulation as they preserve and protect the drug formulation from microbial contamination and drug deterioration due to change in pH, which if unchecked would result into serious adverse effects. Tremendous research is taking place with surfactants where cationic surfactants are developed in different micelle concentration for enhancing drug delivery.
Centre for Disease Control and Prevention states that in the United States 7 in 10 people suffer with health complications and immediately require medical intervention. Rising prevalence of health complications and domicile of market leaders manufacturing topical excipients buttress the growth of topical excipients in North America. Western Europe is pioneering in producing high quality topical excipients with pharmaceutical companies investing huge in accelerated stability testing studies of drug formulation. Asia Pacific is an attractive market destination for topical excipients on account of large ailing population, huge production of generic drug formulation and establishment of major pharmaceutical players engaged in production of branded drugs supports the Asian Pacific market growth.
Historical & Forecast Period
This study report represents analysis of each segment from 2022 to 2032 considering 2023 as the base year. Compounded Annual Growth Rate (CAGR) for each of the respective segments estimated for the forecast period of 2024 to 2032.
The current report comprises of quantitative market estimations for each micro market for every geographical region and qualitative market analysis such as micro and macro environment analysis, market trends, competitive intelligence, segment analysis, porters five force model, top winning strategies, top investment markets, emerging trends and technological analysis, case studies, strategic conclusions and recommendations and other key market insights.
Research Methodology
The complete research study was conducted in three phases, namely: secondary research, primary research, and expert panel review. key data point that enables the estimation of Topical Excipients market are as follows:
Market forecast was performed through proprietary software that analyzes various qualitative and quantitative factors. Growth rate and CAGR were estimated through intensive secondary and primary research. Data triangulation across various data points provides accuracy across various analyzed market segments in the report. Application of both top down and bottom-up approach for validation of market estimation assures logical, methodical and mathematical consistency of the quantitative data.
ATTRIBUTE | DETAILS |
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Research Period | 2022-2032 |
Base Year | 2023 |
Forecast Period | 2024-2032 |
Historical Year | 2022 |
Unit | USD Million |
Segmentation | |
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Function
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Region Segment (2022-2032; US$ Million)
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Key questions answered in this report